97 research outputs found

    Love and Lonergan\u27s Cognitional-Intentional Anthropology: An Inquiry on the Question of a Fifth Level of Consciousness

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    This dissertation addresses a controversial question among those who study the work of Bernard J.F. Lonergan, SJ (1904-1984): To what extent and with what intent did Lonergan affirm a fifth level of consciousness? He used the spatial image of levels of consciousness to express the relations among key operations of the conscious human subject, and the image remains common currency for those familiar with his work. However, the precise number of levels shifted and developed throughout Lonergan\u27s career, beginning with three, moving to four, and finally including some mention of a fifth. As the level of love, this fifth level would seem to play a central role in theology, but if one affirms both the theological centrality of love and the importance of Lonergan\u27s analysis of human subjectivity, then the lack of a full, systematic presentation of the fifth level of human subjectivity hampers the development of systematic theology. Lonergan\u27s own comments on the topic did not give that full understanding, as evidenced by the controversy among Lonergan scholars, and there is a demand for a sustained effort to understand and evaluate Lonergan\u27s understanding of the relation of the fifth level of love to human subjectivity. The first half of this study examines Lonergan\u27s own work on the matter. In a chronological arrangement, Chapters One, Two, and Three engage both published and unpublished primary materials in which Lonergan developed his thought on love and its relation to intentional consciousness. The second half of this study moves beyond Lonergan\u27s contribution and into the contemporary controversy. Chapter Four synthesizes Lonergan\u27s development. Chapter Five addresses and evaluates major works in the controversy in the light of Lonergan\u27s whole development on the matter. Chapter Six suggests an account of the fifth level of consciousness that brings to theology a systematic understanding of the relations between love and subjectivity. Ultimately, it is affirmed that human subjectivity is constituted, in part, by a fifth level of consciousness that is a realm of interpersonal relations, which, when fully authentic, is the subjective locus of self-transcending human subjects in community

    Foundations in Wisconsin: A Directory [30th ed. 2011]

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    The 2011 edition of Foundations in Wisconsin marks the 30th production of the print directory and the 11th year of the online version (www.wifoundations.org). The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. Additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. While the national economic downturn has had a negative effect on Wisconsin foundations the past two years, there are some positive signs of recovery. The total number of active grantmaking foundations increased to a record high 1,324 (with 67 new foundations identified), and the total assets increased by 11% over last year to 6.2billion.However,totalgrantsfellto6.2 billion. However, total grants fell to 458 million, a 3% decrease from last year.https://epublications.marquette.edu/lib_fiw/1006/thumbnail.jp

    Foundations in Wisconsin: A Directory [25th ed. 2006]

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    The 2006 production of Foundations in Wisconsin marks the 25th edition of the print directory and the 6th year of the online version (www.wifoundations.org). The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. However, additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. Wisconsin foundations have shown continued growth in several key areas. The number of active grantmaking foundations has risen to 1227, with 77 new foundations identified since last year’s publication. Total grants increased by 15% to a total of 452million,whileassetsincreasedby6452 million, while assets increased by 6% to 5.5 billion.https://epublications.marquette.edu/lib_fiw/1004/thumbnail.jp

    Foundations in Wisconsin: A Directory [27th ed. 2008]

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    The 2008 release of Foundations in Wisconsin marks the 27th edition of the print directory and the 8th year of the online version (www.wifoundations.org). The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. However, additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. Wisconsin foundations have shown continued growth in key areas. The number of active grantmaking foundations has risen to an all-time high of 1,275, with 70 new foundations identified since last year’s publication. While the total grants remained stable at 475million,thetotalassetsincreasedby16.5475 million, the total assets increased by 16.5% to 7.2 billion.https://epublications.marquette.edu/lib_fiw/1002/thumbnail.jp

    Foundations in Wisconsin: A Directory [29th ed. 2010]

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    The 2010 production of Foundations in Wisconsin marks the 29th edition of the print directory and the 10th anniversary of the online version (www.wifoundations.org). The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. Additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. The nation’s economic downturn continued to have a negative effect on Wisconsin foundations. While the total number of active grantmaking foundations increased to a record high 1,314 (with 123 new foundations identified), the total grants and assets declined to pre-2007 amounts. Total grants decreased by 7% to $473 million, total assets decreased by 18% to 5.6 billion.https://epublications.marquette.edu/lib_fiw/1001/thumbnail.jp

    Foundations in Wisconsin: A Directory [26th ed. 2007]

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    The 2007 edition of Foundations in Wisconsin marks the 26th release of the print directory and the 7th year of the online version (www.wifoundations.org). The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. However, additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. Wisconsin foundations continue to grow in the following key areas: number, grants, and particularly assets. Active grantmaking foundations now number 1,251, with 73 new foundations identified since last year’s publication, resulting in a 25% increase over the past 10 years. Over the past year, total grants increased by 5.8% to a total of almost 479million,whileassetsincreasedby12.5479 million, while assets increased by 12.5% to 6.2 billion.https://epublications.marquette.edu/lib_fiw/1003/thumbnail.jp

    Foundations in Wisconsin: A Directory [28th ed. 2009]

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    The 2009 edition of Foundations in Wisconsin marks the 28th production of the print directory and the 9th year of the online version. The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. However, additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. Wisconsin foundations have continued to grow in key areas even with the economic downturn. Active grantmaking foundations now number 1,286, with 54 new foundations identified. Total grants increased to an all-time high of 507million,a7507 million, a 7% increase over last year. Not surprisingly though, the depressed economy did affect the total assets which decreased by 6% to 6.8 billion.https://epublications.marquette.edu/lib_fiw/1000/thumbnail.jp

    Dynamic contrast-enhanced computed tomography perfusion parameters of canine suspected brain tumors at baseline and during radiotherapy might be different depending on tumor location but not associated with survival

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    IntroductionTreatment of brain tumors in dogs can be associated with significant morbidity and reliable prognostic factors are lacking. Dynamic contrast-enhanced computed tomography (DCECT) can be used to assess tumor perfusion. The objectives of this study were to assess perfusion parameters and change in size of suspected brain tumors before and during radiotherapy (RT) depending on their location and find a potential correlation with survival.MethodsSeventeen client-owned dogs with suspected brain tumors were prospectively recruited. All dogs had a baseline DCECT to assess mass size, blood volume (BV), blood flow (BF), and transit time (TT). Twelve dogs had a repeat DCECT after 12 Gy of megavoltage RT. Survival times were calculated.ResultsIntra-axial masses had lower BF (p = 0.005) and BV (p p = 0.001) and BV (p = 0.004) than extra-axial masses. The volume of the mass was positively associated with TT (p = 0.001) but not with BF and BV. Intra-axial masses showed a more marked decrease in size than extra-axial and pituitary masses during RT (p = 0.022 for length, p = 0.05 for height). Extra-axial masses showed a greater decrease in BF (p = 0.011) and BV (p = 0.012) during RT than pituitary masses and intra-axial masses. Heavier dogs had a shorter survival time (p = 0.011). Perfusion parameters were not correlated with survival.ConclusionDCECT perfusion parameters and change in size of brain masses during RT might be different based on the location of the mass

    Dynamic contrast-enhanced computed tomography in dogs with nasal tumors

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    BackgroundTreatment of nasal tumors in dogs is associated with high morbidity and reliable prognostic factors are lacking. Dynamic contrast-enhanced computed tomography (DCECT) can be used to assess tumor perfusion.ObjectivesTo assess perfusion parameters of nasal tumors (correlating with tumor type) before and during radiotherapy (RT) and find potential correlation with survival.AnimalsTwenty-four client-owned dogs with nasal tumors, including 16 epithelial tumors and 8 sarcomas.MethodsProspective cross-sectional study. All dogs had baseline DCECT to assess fractional vascular volume (BV), blood flow (BF), and transit time (TT). Thirteen dogs had repeat DCECT after 12 Gy of megavoltage RT. Survival times were calculated.ResultsMedian BV was 17.83 mL/100 g (range, 3.63-66.02), median BF was 122.63 mL/100 g/minute (range, 23.65-279.99), and median TT was 8.91 seconds (range, 4.57-14.23). Sarcomas had a significantly lower BF than adenocarcinomas (P = .002), carcinomas (P = .01), and other carcinomas (P = .001), and significantly lower BV than adenocarcinomas (P = .03) and other carcinomas (P = .004). Significant associations were found between epithelial tumors and sarcoma for change in tumor volume (P = .01), width (P = .004), and length (P = .02) in that epithelial tumors decreased in volume whereas sarcomas increased in volume. Perfusion parameters were not correlated with survival.Conclusions and clinical importanceNasal sarcomas have lower BV and BF than nasal carcinomas, and sarcomas have a lower size reduction than carcinomas early on during RT. Baseline results and changes in perfusion parameters may not be correlated with survival

    Copy-number variations in DISC1 and DISC1-interacting partners in major mental illness

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    Robust statistical, genetic and functional evidence supports a role for DISC1 in the etiology of major mental illness. Furthermore, many of its protein-binding partners show evidence for involvement in the pathophysiology of a range of neurodevelopmental and psychiatric disorders. Copy-number variants (CNVs) are suspected to play an important causal role in these disorders. In this study CNV-analysis of DISC1 and its binding partners PAFAH1B1, NDE1, NDEL1, FEZ1, MAP1A, CIT and PDE4B in Scottish and Northern Swedish population-based samples was carried out using multiplex amplicon quantification (MAQ). We report finding rare CNVs in DISC1, NDE1 (together with adjacent genes within the 16p13.11 duplication), NDEL1 (including the overlapping MYH10 gene) and CIT. Our findings provide further evidence for involvement of DISC1 and its interaction partners in neuropsychiatric disorders and also for a role of structural variants in the etiology of these devastating diseases
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